Pathology Specimen Handbook

Recent changes for all departments


 Recent changes for AMINO ACIDS (URINE)

Recent changes for AMINO ACIDS (URINE)
DateFieldChanged FromChanged To
6th January 2026Request GroupUMET, UCRSUMET1, UCRS

 Recent changes for BETA HYDROXY BUTYRATE (INPATIENT)

Recent changes for BETA HYDROXY BUTYRATE (INPATIENT)
DateFieldChanged FromChanged To
29th October 2025Request GroupWB3OHBn/a
Volume (Adults)null mL
Minimum/Paediatric Volumenull mL
29th October 2025Volume (Adults)null mL
Minimum/Paediatric Volumenull mL
29th October 2025Volume (Adults)null mL
Minimum/Paediatric Volumenull mL

 Recent changes for BILE ACIDS (FASTING)

Recent changes for BILE ACIDS (FASTING)
DateFieldChanged FromChanged To
17th September 2025Alternative namesTOTAL BILE ACIDS FASTING
Request GroupBILE1TBAF

 Recent changes for BILE ACIDS (NON FASTING)

Recent changes for BILE ACIDS (NON FASTING)
DateFieldChanged FromChanged To
17th September 2025Alternative namesBILE SALTSBILE SALTS, TOTAL BILE ACIDS NON FASTING
Request GroupBILENF1TBANF

 Recent changes for CADASIL syndrome

Recent changes for CADASIL syndrome
DateFieldChanged FromChanged To
27th August 2025Minimum/Paediatric Volumenull mL

 Recent changes for CD40L (CD154) ASSAY

Recent changes for CD40L (CD154) ASSAY
DateFieldChanged FromChanged To
22nd December 2025Volume (Adults)5 mL2 mL
Minimum/Paediatric Volume2 mL0.6 mL
Collection & Request Instructions

Specimens must be collected between the hours of 3pm on Mondays to 8.30am on Tuesdays and sent immediately to Clayton Pathology Reception for courier to reach The Royal Children's Hospital before 11am on Tuesdays only.

This test is an appointment only test and must be prearranged prior to collection. Please discuss with the immunopathologist on-call (via switch, Teams or Baret) prior to collection. Specimens must be collected at Midday, on the day prior to the booking.

FrequencyTuesdayOn request

 Recent changes for CDKN1C

Recent changes for CDKN1C
DateFieldChanged FromChanged To
30th December 2025Request GroupGENTRANGMPTRAN
8th December 2025Request GroupGMPTRANGENTRAN

 Recent changes for CHOLECALCIFEROL

Recent changes for CHOLECALCIFEROL
DateFieldChanged FromChanged To
6th January 2026Alternative namesVITAMIN D 3, VITAMIN D (25 OH), VITAMIN DVITAMIN D, VITAMIN D 3, VITAMIN D (25 OH), VITAMIN D (25-HYDROXY)

 Recent changes for Complement Function

Recent changes for Complement Function
DateFieldChanged FromChanged To
17th November 2025Assay nameCH50Complement Function
Alternative namesTOTAL HAEMOLYTIC COMPLEMENT, HAEMOLYTIC COMPLEMENT, CH100, COMPLEMENT FUNCTIONAL ASSAYSComplement Function, Total Haemolytic Complement, Haemolytic Complement, CH100, Complement Functional Assays, AH50
Collection & Request Instructions

Complement Functional assays includes Classical (CH50), Alternative (AH50) and Mannose Binding Lactin Pathways.

These test should be performed on the same non gel SST Serum tube (absolute minimum volume 3 mL of blood).

Complement Function testing includes Classical (CH50), Alternative (AH50) and Mannose Binding Lactin Pathways.

Three aliquots in equal amounts (500uL) are required and must be obtained from the same non gel SST Serum tube (absolute minimum required volume is 3 mL of blood). 

 Recent changes for CSF (CEREBRAL SPINAL FLUID) FOR MICROSCOPY & CULTURE

Recent changes for CSF (CEREBRAL SPINAL FLUID) FOR MICROSCOPY & CULTURE
DateFieldChanged FromChanged To
20th January 2026Alternative namesCSFCSF, CSF Cell Count
Minimum/Paediatric Volumenull mL

 Recent changes for CSF - CYTOSPIN MORPHOLOGY (HAEMATOLOGY)

Recent changes for CSF - CYTOSPIN MORPHOLOGY (HAEMATOLOGY)
DateFieldChanged FromChanged To
29th September 2025Assay nameCSF - CYTOSPIN / (HAEM CYTOLOGY)CSF - CYTOSPIN MORPHOLOGY (HAEMATOLOGY)
Alternative namesCSFH CSFH Cytospin Morphology
Request GroupCSFM CSFHCSFH (Add CSFM if 'cell count' is also requested)
Volume (Adults)null mL
Minimum/Paediatric Volumenull mL

 Recent changes for CYP21A2

Recent changes for CYP21A2
DateFieldChanged FromChanged To
2nd September 2025Volume (Adults)4 mL3 mL
Minimum/Paediatric Volume4 mL2 mL
2nd September 2025Preferred Container TypeEDTA - GeneticsEDTA Whole Blood

 Recent changes for CYSTINE (WHITE CELLS)

Recent changes for CYSTINE (WHITE CELLS)
DateFieldChanged FromChanged To
13th February 2026Minimum/Paediatric Volume8 mL10 mL
Collection & Request Instructions

Sample volume MUST be 5 mL or sample will be rejected and recollection requested.

Must be collected at least 8hrs post dose.

Must be pre booked by requesting doctor to the Special Chem Lab Ext: 44516 during business hours. DO NOT BOOK ON MONDAY OR FRIDAY.

Enquires to Chemical Pathologist. Ext 44522

Sample volume MUST be 10 mL or sample will be rejected and recollection requested.

Must be collected at least 8hrs post dose.

Must be pre booked by requesting doctor to the Special Chem Lab Ext: 44516 during business hours. DO NOT BOOK ON MONDAY OR FRIDAY.

Enquires to Chemical Pathologist. Ext 44522

 Recent changes for Dihydropyrimidine Dehydrogenase Genotyping

Recent changes for Dihydropyrimidine Dehydrogenase Genotyping
DateFieldChanged FromChanged To
7th January 2026Minimum/Paediatric Volumenull mL

 Recent changes for Duchenne/Becker muscular dystrophy

Recent changes for Duchenne/Becker muscular dystrophy
DateFieldChanged FromChanged To
27th August 2025Minimum/Paediatric Volumenull mL

 Recent changes for DYT1 dystonia

Recent changes for DYT1 dystonia
DateFieldChanged FromChanged To
27th August 2025Minimum/Paediatric Volumenull mL

 Recent changes for Exome Sequencing (Prenatal)

Recent changes for Exome Sequencing (Prenatal)
DateFieldChanged FromChanged To
29th August 2025Assay nameExome Sequencing (Prenatals)Exome Sequencing (Prenatal)
Alternative namesExome Sequencing
Volume (Adults)null mL
Minimum/Paediatric Volumenull mL

 Recent changes for Familial Hemiplegic Migraine Type 1

Recent changes for Familial Hemiplegic Migraine Type 1
DateFieldChanged FromChanged To
27th August 2025Minimum/Paediatric Volumenull mL

 Recent changes for GLUT1 deficiency syndrome 1

Recent changes for GLUT1 deficiency syndrome 1
DateFieldChanged FromChanged To
27th August 2025Alternative namesAortopathy panel, Cardiac panel

 Recent changes for IMIPRAMINE

Recent changes for IMIPRAMINE
DateFieldChanged FromChanged To
8th October 2025Alternative namesTofranil, Pertofran, Desipramine
Request GroupMISCBIMISCBIO
Volume (Adults)null mL
Minimum/Paediatric Volume3 mL
Optional Container TypeSerum (No Gel)
Heparin Plasma (No Gel)
EDTA Plasma
Collection & Request InstructionsNot routinely available in Victoria. Refer all requests to Duty Biochemist

Trough level is taken up to 1 hour before next dose.

Note the dose and time of dose on the collection form.

FrequencyWeekly

 Recent changes for JAK2 Exon 14

Recent changes for JAK2 Exon 14
DateFieldChanged FromChanged To
26th August 2025Collection & Request Instructions

Please collect the specimen in a separate tube. The specimen must not be used for other testing. This is a DNA test and removal of specimen for other tests may cause the specimen to become contaminated. The same tube can be used for the JAK2 exon 12 test.

 

Please collect the specimen in a separate tube. The specimen must not be used for other testing. This is a DNA test and removal of specimen for other tests may cause the specimen to become contaminated. 

 

 Recent changes for MENINGITIS ENCEPHALITIS PATHOGENS PCR

Recent changes for MENINGITIS ENCEPHALITIS PATHOGENS PCR
DateFieldChanged FromChanged To
30th September 2025Assay nameLISTERIA PCRMENINGITIS ENCEPHALITIS PATHOGENS PCR
Alternative namesLISTERIA MONOCYTOGENES PCR, BIOFIRE, MENINGITIS ENCEPHALITIS PATHOGENS PCRLISTERIA MONOCYTOGENES PCR, BIOFIRE, LISTPCR
Request GroupLISTPCRBIOFIRE
FrequencyMonday
Wednesday
Friday
Mon-Fri

 Recent changes for MND/SMA panel

Recent changes for MND/SMA panel
DateFieldChanged FromChanged To
27th August 2025Minimum/Paediatric Volumenull mL

 Recent changes for Motor neuron disease gene panel

Recent changes for Motor neuron disease gene panel
DateFieldChanged FromChanged To
27th August 2025Alternative namesMotor neurone disease, ALS, Amyotrophic lateral sclerosis, ALS, MND, Lou Gehrig's DiseaseMotor neurone disease, ALS, Amyotrophic lateral sclerosis, ALS, MND, Lou Gehrig's Disease
Minimum/Paediatric Volumenull mL

 Recent changes for NEUROMYELITIS OPTICA AUTOANTIBODY (CSF)

Recent changes for NEUROMYELITIS OPTICA AUTOANTIBODY (CSF)
DateFieldChanged FromChanged To
22nd January 2026Volume (Adults)2 mL0.3 mL
Minimum/Paediatric Volume0.50 mL0.3 mL

 Recent changes for NEUTROPHIL OXIDATIVE BURST

Recent changes for NEUTROPHIL OXIDATIVE BURST
DateFieldChanged FromChanged To
4th December 2025Collection & Request Instructions

For Monday to Friday collection only. Any exceptions to this must be discussed with the immunopathologist on-call.

Must be performed within 24 hours of collection.

For Monday to Thursday (all day), and Friday (am only) collection. Any exceptions to this must be discussed with the immunopathologist on-call.

Must be performed within 24 hours of collection.

 Recent changes for NT-PRO-BNP

Recent changes for NT-PRO-BNP
DateFieldChanged FromChanged To
4th December 2025Request GroupNTPBNP1NTBNP
4th December 2025FrequencyDailyMon-Fri
8th October 2025Volume (Adults)2 mL4 mL
Minimum/Paediatric Volume1 mL4 mL
Preferred Container TypeSerum - Gel tube - Contains Clot ActivatorHeparin Plasma (Gel)
Optional Container TypeHeparin Plasma (Gel)Serum - Gel tube - Contains Clot Activator
Collection & Request Instructions

Minimum sample volume 500 uL of sample.

FrequencyOn requestDaily

 Recent changes for Pharmacogenetic Testing

Recent changes for Pharmacogenetic Testing
DateFieldChanged FromChanged To
7th November 2025Alternative namesPharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1, PGx, Gilbert'sPharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1, PGx, Gilbert's
20th October 2025Alternative namesPharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1, PGx, Gilbert'sPharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1, PGx, Gilbert's
20th October 2025Alternative namesPharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1, PGx, TPMT, Gilbert'sPharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1, PGx, Gilbert's
Request GroupMISCBIOMISCGEN
20th October 2025Alternative namesPharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1, PGx, TPMT, Gilbert'sPharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1, PGx, TPMT, Gilbert's
20th October 2025Alternative namesPharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1, PGx, TPMT, Gilbert'sPharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1, PGx, TPMT, Gilbert's
Collection & Request Instructions

1814_GD_PGx_DrBrochure

20th October 2025Alternative namesPharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1Pharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1, PGx, TPMT, Gilbert's
Collection & Request Instructions

Refer to Pharmacogenomics information

Pharmacogenetic (PGx) Testing | Clinical Labs - Australian Clinical Labs

FrequencyOn request
27th August 2025Assay nameCYTOCHROME P450Pharmacogenetic Testing
Alternative namesPharmacogenomics, CP450Pharmacogenomics, Cytochrome P450, CYP2D6, CYP2C19, CYP2C9, SLCO1B1
Collection & Request Instructions

Refer to Pharmacogenomics Profile

Refer to Pharmacogenomics information

Pharmacogenetic (PGx) Testing | Clinical Labs - Australian Clinical Labs

 Recent changes for QUANTIFERON-TB GOLD PLUS ASSAY

Recent changes for QUANTIFERON-TB GOLD PLUS ASSAY
DateFieldChanged FromChanged To
16th January 2026Collection & Request Instructions

Requires QuantiFERON-TB Gold Plus Blood Collection Tubes set of four.

Collect exactly  1 mL into each tube. Testing cannot be performed if incorrect volume is collected.

Use black square on label for reference. Refer to photograph for order of draw and volume indication. Mix gently by turning tube end-over end X10 ensuring that the entire inner surface of the tube has been coated in blood.

EMR and MediPATH labels can be adhered to the QGT tubes in ANY order. All 4 x tubes MUST be labelled. Microbiology staff will process the samples according to tube type/colour.

Send to laboratory immediately after collection.

Preferred collection: Monday to Friday between 0900-1600 hours.

Please answer question if patient is immunosuppressed.

If non-MBS then non CMBS test

DO NOT STORE IN FRIDGE BEFORE SENDING

Requires QuantiFERON-TB Gold Plus Blood Collection Tubes set of four.

Collect exactly  1 mL into each tube. Testing cannot be performed if incorrect volume is collected.

Use black square on label for reference. Refer to photograph for order of draw and volume indication. Mix gently by turning tube end-over end X10 ensuring that the entire inner surface of the tube has been coated in blood.

EMR and MediPATH labels can be adhered to the QGT tubes in ANY order. All 4 x tubes MUST be labelled. Microbiology staff will process the samples according to tube type/colour.

Send to laboratory immediately after collection.

Preferred collection: Monday to Thursday between 0900-1600 hours.

Please answer question if patient is immunosuppressed.

If non-MBS then non CMBS test

DO NOT STORE IN FRIDGE BEFORE SENDING

 Recent changes for SPECIFIC IGE (sIGE) FOR ALLERGEN

Recent changes for SPECIFIC IGE (sIGE) FOR ALLERGEN
DateFieldChanged FromChanged To
4th December 2025Alternative namesRAST FOR XX WHERE XX REPRESENTS THE ALLERGEN (e.g. ASPERGILLUS), OMEGA-5-GLIADINRAST FOR XX WHERE XX REPRESENTS THE ALLERGEN (e.g. ASPERGILLUS), OMEGA-5-GLIADIN, ALPHA-GAL
Collection & Request Instructions

Volume of blood required is dependent on the number of allergens requested.  At least 1mL of blood is required per allergen.

A maximum of 4 specific allergens or mixes for each request in a 12 month period.

Volume of blood required is dependent on the number of allergens requested.  At least 1mL of blood is required per allergen.

Please note to advise patients that out of pocket costs may be incurred including, but not limited to, instances where more than: 4 single allergens OR 2 mixes OR 1 mix/2 single allergens are requested. Pricing varies according to referral testing laboratory and allergens requested. 

 Recent changes for Spinal and bulbar muscular atrophy

Recent changes for Spinal and bulbar muscular atrophy
DateFieldChanged FromChanged To
27th August 2025Alternative namesKennedy' Disease, X-linked type 1 AR known gene variant testing, SMAX1, SBMA, ARKennedy' Disease, X-linked type 1 AR known gene variant testing, SMAX1, SBMA, AR

 Recent changes for Spinocerebellar ataxia (SCA) Panel Test

Recent changes for Spinocerebellar ataxia (SCA) Panel Test
DateFieldChanged FromChanged To
19th January 2026Alternative namesSpinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia Type 6, Spinocerebellar Ataxia Type 7, Spinocerebellar Ataxia Type 12, Spinocerebellar Ataxia Type 17Spinocerebellar Ataxia Type 1, Spinocerebellar Ataxia Type 2, Spinocerebellar Ataxia Type 3, Spinocerebellar Ataxia Type 6, Spinocerebellar Ataxia Type 7, Spinocerebellar Ataxia Type 12, Spinocerebellar Ataxia Type 15, Spinocerebellar Ataxia Type 17

 Recent changes for T CELL PROLIFERATION

Recent changes for T CELL PROLIFERATION
DateFieldChanged FromChanged To
9th October 2025Collection & Request Instructions

Please note, this test is indicated for the exclusion of primary immunodeficiency only. Reconsider ordering in the context of organ transplantation or secondary immunodeficiency, including patients on immunosuppressants.

This test is only performed on Tuesday, with special collection and transport requirements. Please liaise with the Immunopathologist On-call prior to request or collection.

Please note, this test is indicated for the exclusion of primary immunodeficiency only. Reconsider ordering in the context of organ transplantation or secondary immunodeficiency, including patients on immunosuppressants.

This test is only performed on Tuesday, with special collection and transport requirements. Please liaise with the Immunopathologist On-call prior to requesting or blood collection.

Uncontrolled when downloaded or printed.
Date printed: 14th February, 2026 05:49:09